.

.
Library of Professor Richard A. Macksey in Baltimore

POSTS BY SUBJECT

Labels

Thursday, July 8, 2010

population in Xinjiang

 

Origins of the Uighur

Interesting bit from the paper:
Notably, the distribution of admixture proportions among UIG individuals is relatively even, with 48.7% the lowest admixture from European ancestry and the highest 62.2%. The standard deviation is only 3.8%, which is much smaller than the estimation for the African-American (AfA) population,58 suggesting a much longer history of admixture events for the Uyghur population compared with the AfA population.


The American Journal of Human Genetics, doi:10.1016/j.ajhg.2008.01.017

Analysis of Genomic Admixture in Uyghur and Its Implication in Mapping Strategy

Shuhua Xu et al.

Abstract

The Uyghur (UIG) population, settled in Xinjiang, China, is a population presenting a typical admixture of Eastern and Western anthropometric traits. We dissected its genomic structure at population level, individual level, and chromosome level by using 20,177 SNPs spanning nearly the entire chromosome 21. Our results showed that UIG was formed by two-way admixture, with 60% European ancestry and 40% East Asian ancestry. Overall linkage disequilibrium (LD) in UIG was similar to that in its parental populations represented in East Asia and Europe with regard to common alleles, and UIG manifested elevation of LD only within 500 kb and at a level of 0.1 < style="font-weight: bold;">we estimated that the admixture event of UIG occurred about 126 [107∼146] generations ago, or 2520 [2140∼2920] years ago assuming 20 years per generation. In spite of the long history and short LD of Uyghur compared with recent admixture populations such as the African-American population, we suggest that mapping by admixture LD (MALD) is still applicable in the Uyghur population but ∼10-fold AIMs are necessary for a whole-genome scan.

Ancient mtDNA from Sampula population in Xinjiang

From the paper:
Physical anthropology of Shao et al. revealed that the ancient human bones from Sampula exhibited primarily Mongoloid characteristics with certain European features, but Han et al. believed that Sampula populations are mainly of European character and actually are close to that of the Eastern Mediterranean type.

...

In conclusion, the analysis of mtDNA haplogroup distribution showed that the ancient Sampula was a complex population of European and Asian, corresponding to the physical anthopology result of Shao et al.

Progress in Natural Science, Volume 17, Issue 8 August 2007 , pages 927 - 933

Mitochondrial DNA analysis of ancient Sampula population in Xinjiang

Chengzhi Xie et al.

Abstract

The archaeological site fo Sampula cemetery was located about 14 km to the southwest of the Luo County in Xinjiang Khotan, China, belonging to the ancient Yutian kingdom. 14C analysis showed that this cemetery was used from 217 B.C. to 283 A. D. Ancient DNA was analysed by 364 bp of the mitochondrial DNA hypervariable region 1 (mtDNA HVR-1), and by six restriction fragment length polymorphism (RFLP) sites of mtDNA coding region. We successfully extracted and sequenced intact stretches of maternally inherited mtDNA from 13 out of 16 ancient Sampula samples. The analysis of mtDNA haplogroup distribution showed that the ancient Sampula was a complex population with both European and Asian Characteristics. Median joining network of U3 sub-haplogroup and multi-dimensional scaling analysis all showed that the ancient Sampula had maternal relationship with Ossetian and Iranian.

No comments:

Post a Comment