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Thursday, August 2, 2012

Hoffer - Treatment of Alcoholism with Psychedelic Therapy


Treatment of Alcoholism with Psychedelic Therapy

    Abram Hoffer

        From: PSYCHEDELICS, The Uses and Implications of Psychedelic Drugs
        
edited by Bernard Aaronson and Humphry Osmond Doubleday & Company, 1970.
        ©Aaronson & Osmond.


Introduction


    Alcoholics Anonymous, the great self-help group-therapy movement, is the only established treatment for alcoholics. Until much more is known about the personal (biochemical and psychological), familial, and social factors that contribute to alcoholism, so it will remain. Most new therapies are merely adjunctive to AA and will continue to be so until it is shown that they have therapeutic value when used alone. In my view, psychedelic therapy is best used as a preparation for AA.
    When Bill W. and Dr. Bob founded AA, alcoholism had not been accepted as a disease, either by society at large or by the medical profession. Society considered it a moral problem, but found itself confronted with an interesting dilemma, for only a small proportion of the total drinking society drank excessively. No moral sanctions were required for the majority, who eventually made social drinking an integral part of the culture.
    The majority who remained moral drinkers could not understand why a minority became intemperate or alcoholic. Moral sanctions were applied on the premise that excessive drinking arose from defects of character, defects of will, and defects in society. These sanctions included education, persuasion, incarceration, and banishment. Unfortunately, the most stringent measures had little permanent effect, and the proportion of the drinking society (a concept developed by Dr. H. Osmond) remained the same or increased. Medicine also considered alcoholism a non-disease.
    The founders of AA introduced the medical model first to alcoholics, later to society, and finally to the medical profession. This concept was very appealing to alcoholics because it gave them a satisfactory explanation for their misfortunes. If they were sick and not evil, then they might expect the same sort of treatment they would receive if they developed pneumonia or diabetes. Bill W. and Dr. Bob also introduced the concept of allergy, which thirty-five years ago was incorporated into medicine as a new group of diseases. (1)
    But AA insisted that alcoholism was more than a physical illness. It also carried strong personal responsibility. An alcoholic could not be censured for being an alcoholic, but he could be for doing nothing about it.
    Society resisted the idea that alcoholics are sick, since it got no guidance from a reluctant medical profession. Doctors expect diseases to be more or less definable, to have treatment that may be ineffective but must be in common use, and to have a predictable prognosis. When they became convinced that AA did help large numbers of alcoholics remain sober, they gradually accepted alcoholics as patients. Even now, the majority of hospitals are extremely reluctant to admit alcoholics who are drunk, and many doctors dread seeing them in their offices. Eventually AA forced the profession to accept the fact that alcoholism, which has been estimated to afflict 5 per cent of the population, is a disease. This marked the beginning of the final solution to the problem. For, having accepted the disease concept, doctors were challenged by the enormous problems, and, in a matter of a few years, several major therapeutic discoveries were made.
    The newer adjunctive therapies developed for alcoholism may be divided into the psychological and the biochemical. Psychotherapy, deconditioning therapy, and psychedelic therapy are examples of purely psychological therapy, while sugar-free diets for relative hypoglycemia, mega vitamin B3, megascorbic acid, and adrenocortical extracts (or extracts of licorice) are examples of pure chemotherapies.
    Psychedelic therapy is the only therapy that has prepared alcoholics to become responsible members of AA, when previously they had been unable to do so.

Psychedelic Therapy

    We must distinguish sharply between psychedelic reactions and the means for inducing them. Failure to understand this distinction has led to several futile researches, best exemplified by the study of Smart and Storm (1964), which was widely circulated in an extreme form before publication of the watered-down version.
    Psychedelic therapy refers to a form of psychotherapy in which hallucinogenic drugs are used in a particular way to facilitate the final goal, which for alcoholics is sobriety. The drugs may be mescaline, LSD, psilocybin, and many others, as well as combinations. It is therefore trivial to test the effect of LSD or other hallucinogens on alcoholics in such a way that there is no psychedelic reaction. In fact, these trivial experiences have led to trivial data, as reported by Smart et al. (1966), who claimed that a group of ten alcoholics given LSD did not differ in outcome from a group of ten given another psychoactive drug. Close examination of their report shows that no therapy was given, nor was there any encouragement of discussion of problems. The experience was not psychedelic, but was more in the nature of an inquisition, with the subject strapped to the bed, pretreated with dilantin, and ill from 800 mcg of LSD. Since no investigator has ever claimed that LSD used in this way does have any therapeutic effect, this experiment suggests that LSD used with no therapeutic intent or skill is not apt to help. One of the subjects given LSD by Smart et al. described his experience in comparison with a psychedelic reaction he received from smaller quantities of LSD in Saskatchewan. The experiences and the outcome were quite different.
    Psychedelic therapy aims to create a set and a setting that will allow proper psychotherapy. The psychedelic therapist works with material that the patient experiences and discusses, and helps him resynthesize a new model of life or a new personal philosophy. During the experience, the patient draws upon information flooding in from the altered environment and from his own past, and uses it to eliminate false ideas and false memories. With the aid of the therapist, he evaluates himself more objectively and becomes more acutely aware of his own responsibility for his situation and, even more important, for doing something about it. He also becomes aware of inner strengths or qualities that help him in his long and difficult struggle toward sobriety.
    The book The Use of LSD in Psychotherapy and Alcoholism, edited by H. A. Abramson (1967), contains the best collection of scientific papers on psychedelic therapy.
    Around 1952, Osmond and I had become familiar with psychotomimetic reactions induced by LSD. There was a marked similarity between these reactions and schizophrenia and the toxic psychoses. Delirium tremens is one of the common toxic states. It occurred to us that LSD might be used to produce models of dt's. Many alcoholics ascribed the beginning of their recovery to "hitting bottom," and often "hitting bottom" meant having had a particularly memorable attack of dt's. We thought that LSD could be used this way with no risk to the patient. We treated our first two alcoholics at the Saskatchewan Hospital, Weyburn, Saskatchewan, and one recovered.
    Other early pilot studies were encouraging, and we increased the tempo of our research until at one time six of our major psychiatric centers in Saskatchewan were using it. As of now, we must have treated close to one thousand alcoholics.
    Within a few years after our first patients were treated, we became aware that a large proportion of our alcoholics did not have psychotomimetic reactions. Their experiences were exciting and pleasant, and yielded insight into their drinking problems. It became evident that a new phenomenon had been recognized in psychiatry. Osmond created the word psychedelic to define these experiences, and announced this at a meeting of the New York Academy of Sciences in 1957.
    Following this, our researches were aimed at improving the quality and quantity of psychedelic reactions. Within the past ten years, major studies, under the direction of Dr. Ross MacLean, Hollywood Hospital, New Westminster, British Columbia, and under the direction of Dr. S. Unger at Spring Grove State Hospital, Baltimore, Maryland, have added materially to our knowledge of the effect of psychedelic therapy on alcoholism.
    I will not review the results of psychedelic therapy in detail. This has been done in the books edited by H. A. Abramson and in The Hallucinogens by A. Hoffer and H. Osmond (1967). The one striking conclusion is that every scientist using psychedelic therapy with alcoholics found the same proportion of recoveries. Whether the experiments were considered controlled or not, about 50 per cent were able to remain sober or to drink much less. This seems to be a universal statistic for LSD therapy.
    (1). Dr. Walter Alvarez recently told me that when he wrote a paper on food allergies at the Mayo Clinic about fifty years ago, he was severely criticized by his colleagues. Only strong support from one of the Mayos, who discovered that he himself had a food allergy, protected Alvarez from even-more-powerful assault. Medicine seems very reluctant to take unto itself new diseases. (back)


    Note: The rest of the paper discusses some technical considerations of the psychedelic therapy method such as contraindications, how to select subjects for psychedelic therapy including various psychological and physiological tests to be used, and a short summary of the method.   —PW

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